About Mpv17-like protein 2
Mpv17-like protein 2 (MPV17L2) is a protein
from Homo sapiens identified by UniProt accession
Q567V2, 206 residues long.
MolForge cross-references it against 0 known binders and
70 disease associations.
Target properties
| Protein name | Mpv17-like protein 2 |
| UniProt accession | Q567V2 |
| Gene | MPV17L2 |
| Organism | Homo sapiens |
| Length | 206 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (70)
Diseases linked to this target (Open Targets).
- multiple sclerosis · score 0.41
- BMI-adjusted waist-hip ratio · score 0.35
- alkaline phosphatase measurement · score 0.30
- lysosomal storage disease · score 0.25
- Alzheimer disease · score 0.25
- neurodegenerative disease · score 0.25
- Parkinson disease · score 0.25
- monocyte count · score 0.25
- calcium measurement · score 0.24
- monocyte percentage of leukocytes · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q567V2-F1 | alphafold | PREDICTED | 87.63 | — |
Amino-acid sequence (206 residues)
MARGGWRRLR RLLSAGQLLF QGRALLVTNT LGCGALMAAG DGVRQSWEIR ARPGQVFDPR RSASMFAVGC SMGPFLHYWY LSLDRLFPAS GLRGFPNVLK KVLVDQLVAS PLLGVWYFLG LGCLEGQTVG ESCQELREKF WEFYKADWCV WPAAQFVNFL FVPPQFRVTY INGLTLGWDT YLSYLKYRSP VPLTPPGCVA LDTRAD
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