Zinc finger protein 385B (ZNF385B)

About Zinc finger protein 385B

Zinc finger protein 385B (ZNF385B) is a protein from Homo sapiens identified by UniProt accession Q569K4, 471 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

Target properties

Protein name	Zinc finger protein 385B
UniProt accession	Q569K4
Gene	ZNF385B
Organism	Homo sapiens
Length	471 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (63)

Diseases linked to this target (Open Targets).

systolic blood pressure · score 0.43
testosterone measurement · score 0.40
sex hormone-binding globulin measurement · score 0.34
sudden cardiac arrest · score 0.31
pulse pressure measurement · score 0.29
blood protein measurement · score 0.28
mannan-binding lectin serine protease 1 measurement · score 0.28
breast milk measurement · score 0.27
mean platelet volume · score 0.11
protein measurement · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q569K4-F1	alphafold	PREDICTED	60.48	—

Amino-acid sequence (471 residues)

MNMANFLRGF EEKGIKNDRP EDQLSKEKKK ILFSFCEVCN IQLNSAAQAQ VHSNGKSHRK RVKQLSDGQP PPPAQASPSS NSSTGSTCHT TTLPALVRTP TLMMQPSLDI KPFMSFPVDS SSAVGLFPNF NTMDPVQKAV INHTFGVSIP PKKKQVISCN VCQLRFNSDS QAEAHYKGSK HAKKVKALDA TKNKPKMVPS KDSAKANPSC SITPITGNNS DKSEDKGKLK ASSSSQPSSS ESGSFLLKSG TTPLPPGAAT SPSKSTNGAP GTVVESEEEK AKKLLYCSLC KVAVNSLSQL EAHNTGSKHK TMVEARNGAG PIKSYPRPGS RLKMQNGSKG SGLQNKTFHC EICDVHVNSE IQLKQHISSR RHKDRVAGKP LKPKYSPYNK LQRSPSILAA KLAFQKDMMK PLAPAFLSSP LAAAAAVSSA LSLPPRPSAS LFQAPAIPPA LLRPGHGPIR ATPASILFAP Y

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards