About E2F-associated phosphoprotein
E2F-associated phosphoprotein (EAPP) is a protein
from Homo sapiens identified by UniProt accession
Q56P03, 285 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | E2F-associated phosphoprotein |
|---|
| UniProt accession | Q56P03 |
|---|
| Gene | EAPP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 285 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- insulin measurement · score 0.20
- genetic disorder · score 0.12
- self reported educational attainment · score 0.07
- diastolic blood pressure · score 0.04
- whole body water mass · score 0.03
- fat body mass · score 0.03
- lean body mass · score 0.02
- ovarian carcinoma · score 0.01
- Alzheimer disease · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q56P03-F1 | alphafold | PREDICTED | 74.70 | — |
Amino-acid sequence (285 residues)
MNRLPDDYDP YAVEEPSDEE PALSSSEDEV DVLLHGTPDQ KRKLIRECLT GESESSSEDE FEKEMEAELN STMKTMEDKL SSLGTGSSSG NGKVATAPTR YYDDIYFDSD SEDEDRAVQV TKKKKKKQHK IPTNDELLYD PEKDNRDQAW VDAQRRGYHG LGPQRSRQQQ PVPNSDAVLN CPACMTTLCL DCQRHESYKT QYRAMFVMNC SINKEEVLRY KASENRKKRR VHKKMRSNRE DAAEKAETDV EEIYHPVMCT ECSTEVAVYD KDEVFHFFNV LASHS
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