Pyrin domain-containing protein 2 (PYDC2)

About Pyrin domain-containing protein 2

Pyrin domain-containing protein 2 (PYDC2) is a protein from Homo sapiens identified by UniProt accession Q56P42, 97 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Pyrin domain-containing protein 2
UniProt accession	Q56P42
Gene	PYDC2
Organism	Homo sapiens
Length	97 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.27
serum metabolite measurement · score 0.18
adolescent idiopathic scoliosis · score 0.16
body height · score 0.04
Behcet's syndrome · score 0.02
squamous cell carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q56P42-F1	alphafold	PREDICTED	74.29	—

Amino-acid sequence (97 residues)

MASSAELDFN LQALLEQLSQ DELSKFKSLI RTISLGKELQ TVPQTEVDKA NGKQLVEIFT SHSCSYWAGM AAIQVFEKMN QTHLSGRADE HCVMPPP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards