About Caspase recruitment domain-containing protein 16
Caspase recruitment domain-containing protein 16 (CARD16) is a protein
from Homo sapiens identified by UniProt accession
Q5EG05, 197 residues long.
MolForge cross-references it against 0 known binders and
84 disease associations.
Target properties
| Protein name | Caspase recruitment domain-containing protein 16 |
|---|
| UniProt accession | Q5EG05 |
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| Gene | CARD16 |
|---|
| Organism | Homo sapiens |
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| Length | 197 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (84)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.23
- interleukin 18 measurement · score 0.17
- schizophrenia · score 0.08
- hepatocellular carcinoma · score 0.08
- head and neck squamous cell carcinoma · score 0.05
- neoplasm · score 0.04
- self reported educational attainment · score 0.03
- risk-taking behaviour · score 0.03
- mathematical ability · score 0.03
- cardiovascular disease · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5EG05-F1 | alphafold | PREDICTED | 64.97 | — |
Amino-acid sequence (197 residues)
MADKVLKEKR KLFIHSMGEG TINGLLDELL QTRVLNQEEM EKVKRENATV MDKTRALIDS VIPKGAQACQ ICITYICEED SYLAETLGLS AALQAVQDNP AMPTCSSPEG RIKLCFLEDA QRIWKQKLQR CHVQNTIIKW SERYTSGSFE MQWLFLRTNF IERFWRNILL LPLHKGSLYP RIPGLGKELQ TGTHKLS
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