Zinc finger protein 789 (ZNF789)

About Zinc finger protein 789

Zinc finger protein 789 (ZNF789) is a protein from Homo sapiens identified by UniProt accession Q5FWF6, 425 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.

Target properties

Protein name	Zinc finger protein 789
UniProt accession	Q5FWF6
Gene	ZNF789
Organism	Homo sapiens
Length	425 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (55)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.32
mean corpuscular hemoglobin concentration · score 0.30
hormone measurement · score 0.20
dehydroepiandrosterone sulphate measurement · score 0.18
sitting height measurement · score 0.13
progesterone measurement · score 0.11
body fat percentage · score 0.10
reticulocyte count · score 0.10
mean platelet volume · score 0.09
age at first sexual intercourse measurement · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5FWF6-F1	alphafold	PREDICTED	68.26	—

Amino-acid sequence (425 residues)

MFPPARGKEL LSFEDVAMYF TREEWGHLNW GQKDLYRDVM LENYRNMVLL GFQFPKPEMI CQLENWDEQW ILDLPRTGNR KASGSACPGS EARHKMKKLT PKQKFSEDLE SYKISVVMQE SAEKLSEKLH KCKEFVDSCR LTFPTSGDEY SRGFLQNLNL IQDQNAQTRW KQGRYDEDGK PFNQRSLLLG HERILTRAKS YECSECGKVI RRKAWFDQHQ RIHFLENPFE CKVCGQAFRQ RSALTVHKQC HLQNKPYRCH DCGKCFRQLA YLVEHKRIHT KEKPYKCSKC EKTFSQNSTL IRHQVIHSGE KRHKCLECGK AFGRHSTLLC HQQIHSKPNT HKCSECGQSF GRNVDLIQHQ RIHTKEEFFQ CGECGKTFSF KRNLFRHQVI HTGSQPYQCV ICGKSFKWHT SFIKHQGTHK GQIST

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards