Probable inactive ribonuclease-like protein 13…

About Probable inactive ribonuclease-like protein 13

Probable inactive ribonuclease-like protein 13 (RNASE13) is a protein from Homo sapiens identified by UniProt accession Q5GAN3, 156 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

Target properties

Protein name	Probable inactive ribonuclease-like protein 13
UniProt accession	Q5GAN3
Gene	RNASE13
Organism	Homo sapiens
Length	156 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (24)

Diseases linked to this target (Open Targets).

portal hypertension · score 0.04
Congenital intrinsic factor deficiency · score 0.04
chronic intestinal pseudoobstruction · score 0.04
immunodeficiency 84 · score 0.04
Ornithine transcarbamylase deficiency · score 0.04
Alpha-1-antitrypsin deficiency · score 0.03
Mantle cell lymphoma · score 0.03
immunoproliferative small intestinal disease · score 0.03
pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 8 · score 0.03
NK-cell enteropathy · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5GAN3-F1	alphafold	PREDICTED	89.46	—

Amino-acid sequence (156 residues)

MAPAVTRLLF LQLVLGPTLV MDIKMQIGSR NFYTLSIDYP RVNYPKGFRG YCNGLMSYMR GKMQNSDCPK IHYVIHAPWK AIQKFCKYSD SFCENYNEYC TLTQDSLPIT VCSLSHQQPP TSCYYNSTLT NQKLYLLCSR KYEADPIGIA GLYSGI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Probable inactive ribonuclease-like protein 13 (RNASE13)