About Inactive ribonuclease-like protein 10
Inactive ribonuclease-like protein 10 (RNASE10) is a protein
from Homo sapiens identified by UniProt accession
Q5GAN6, 216 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Inactive ribonuclease-like protein 10 |
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| UniProt accession | Q5GAN6 |
|---|
| Gene | RNASE10 |
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| Organism | Homo sapiens |
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| Length | 216 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.11
- neurofibrillary tangles measurement · score 0.09
- metabolite measurement · score 0.02
- PHF-tau measurement · score 0.02
- non-small cell lung carcinoma · score 0.01
- aleutian mink disease · score 0.01
- viral disease · score 0.00
- head and neck squamous cell carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5GAN6-F1 | alphafold | PREDICTED | 64.72 | — |
Amino-acid sequence (216 residues)
MKLNLVQIFF MLLMLLLGLG MGLGLGLHMA TAVLEESDQP LNEFWSSDSQ DKAEATEEGD GTQTTETLVL SNKEVVQPGW PEDPILGEDE VGGNKMLRAS ALFQSNKDYL RLDQTDRECN DMMAHKMKEP SQSCIAQYAF IHEDLNTVKA VCNSPVIACE LKGGKCHKSS RPFDLTLCEL SQPDQVTPNC NYLTSVIKKH IIITCNDMKR QLPTGQ
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