About XK-related protein 6
XK-related protein 6 (XKR6) is a protein
from Homo sapiens identified by UniProt accession
Q5GH73, 641 residues long.
MolForge cross-references it against 0 known binders and
115 disease associations.
Target properties
| Protein name | XK-related protein 6 |
|---|
| UniProt accession | Q5GH73 |
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| Gene | XKR6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 641 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (115)
Diseases linked to this target (Open Targets).
- diet measurement · score 0.42
- heel bone mineral density · score 0.41
- systolic blood pressure · score 0.39
- bone quantitative ultrasound measurement · score 0.39
- risk-taking behaviour · score 0.38
- neuroticism measurement · score 0.38
- body mass index · score 0.37
- type 2 diabetes mellitus · score 0.36
- BMI-adjusted waist circumference · score 0.32
- alcohol consumption measurement · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5GH73-F1 | alphafold | PREDICTED | 62.75 | — |
Amino-acid sequence (641 residues)
MAAKSDGGGV GVGFAQLHNL DEAVGSGGEE DGEPGGGGCG GGGDGSEPGE SSSMHICHCC NTSSCYWGCR SACLRSLLGR KPRRSAAADG GDQPLQPPAA PGAGRQPPTP SAARPEPPPP QVERPWLDCL WIVLALLVFF GDVGTDLWLA LDYYRKGDYV YFGLTLFFVL VPSLLVQSLS FRWFVQDYTG GGLGAVEGLT SRGPPMMGAG YVHGAARGGP GVRVSPTPGA QRLCRLSVWI WQSVIHLLQM GQVWRYIRTM YLGIQSQRRK EHQRRFYWAM MYEYADVNML RLLETFLESA PQLVLQLYIM LQKNSAETLP CVSSVTSLMS LAWVLASYHK LLRDSRDDKK SMSYRGAIIQ VFWRLFTISS RVISFALFAS IFQLYFGIFV VVHWCAMAFW IIHGGTDFCM SKWEEILFNM VVGIVYIFCW FNVKEGRTRY RMFAYYTIVL TENAALTFLW YFYRDPETTD SYAVPALCCV FISFVAGIAM MLLYYGVLHP TGPRAKILAS SCCAELLWGI PLPPDVEPMA PEIPGYRGTQ VTPTRAVTEQ QEDLTADTCL PVFQVRPMGP PTPLGRPYLP EGPLIKIDMP RKRYPAWDAH FVDRRLRRTI NILQYVTPTA VGIRYRDGPL LYELLQYESS L
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