About Transcription initiation factor TFIID subunit 7-like
Transcription initiation factor TFIID subunit 7-like (TAF7L) is a protein
from Homo sapiens identified by UniProt accession
Q5H9L4, 462 residues long.
MolForge cross-references it against 0 known binders and
120 disease associations.
Target properties
| Protein name | Transcription initiation factor TFIID subunit 7-like |
|---|
| UniProt accession | Q5H9L4 |
|---|
| Gene | TAF7L |
|---|
| Organism | Homo sapiens |
|---|
| Length | 462 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (120)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.58
- breast adenocarcinoma · score 0.25
- glioblastoma multiforme · score 0.25
- pancreatic adenocarcinoma · score 0.24
- head and neck squamous cell carcinoma · score 0.19
- endometrial cancer · score 0.18
- lung adenocarcinoma · score 0.18
- clear cell renal carcinoma · score 0.17
- small cell lung carcinoma · score 0.14
- chronic lymphocytic leukemia · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5H9L4-F1 | alphafold | PREDICTED | 67.36 | — |
Amino-acid sequence (462 residues)
MECPEGQLPI SSENDSTPTV STSEVTSQQE PQILVDRGSE TTYESSADIA GDEGTQIPAD EDTQTDADSS AQAAAQAPEN FQEGKDMSES QDEVPDEVEN QFILRLPLEH ACTVRNLARS QSVKMKDKLK IDLLPDGRHA VVEVEDVPLA AKLVDLPCVI ESLRTLDKKT FYKTADISQM LVCTADGDIH LSPEEPAAST DPNIVRKKER GREEKCVWKH GITPPLKNVR KKRFRKTQKK VPDVKEMEKS SFTEYIESPD VENEVKRLLR SDAEAVSTRW EVIAEDGTKE IESQGSIPGF LISSGMSSHK QGHTSSEYDM LREMFSDSRS NNDDDEDEDD EDEDEDEDED EDEDKEEEEE DCSEEYLERQ LQAEFIESGQ YRANEGTSSI VMEIQKQIEK KEKKLHKIQN KAQRQKDLIM KVENLTLKNH FQSVLEQLEL QEKQKNEKLI SLQEQLQRFL KK
Explore Transcription initiation factor TFIID subunit 7-like with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets