Cancer/testis antigen family 45 member A1 (CT45A1)

About Cancer/testis antigen family 45 member A1

Cancer/testis antigen family 45 member A1 (CT45A1) is a protein from Homo sapiens identified by UniProt accession Q5HYN5, 189 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.

Target properties

Protein name	Cancer/testis antigen family 45 member A1
UniProt accession	Q5HYN5
Gene	CT45A1
Organism	Homo sapiens
Length	189 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (56)

Diseases linked to this target (Open Targets).

neoplasm · score 0.09
hypertriglyceridemia 2 · score 0.08
cholesterol-ester transfer protein deficiency · score 0.08
cancer · score 0.07
thyroid hormone metabolism, abnormal, 2 · score 0.07
sitosterolemia · score 0.07
Combined hyperlipidemia · score 0.06
homozygous familial hypercholesterolemia · score 0.06
hypercholesterolemia, autosomal dominant, 3 · score 0.05
hyperlipidemia due to hepatic triglyceride lipase deficiency · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5HYN5-F1	alphafold	PREDICTED	68.59	—

Amino-acid sequence (189 residues)

MTDKTEKVAV DPETVFKRPR ECDSPSYQKR QRMALLARKQ GAGDSLIAGS AMSKAKKLMT GHAIPPSQLD SQIDDFTGFS KDRMMQKPGS NAPVGGNVTS SFSGDDLECR ETASSPKSQR EINADIKRKL VKELRCVGQK YEKIFEMLEG VQGPTAVRKR FFESIIKEAA RCMRRDFVKH LKKKLKRMI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards