About Zinc finger protein 831
Zinc finger protein 831 (ZNF831) is a protein
from Homo sapiens identified by UniProt accession
Q5JPB2, 1677 residues long.
MolForge cross-references it against 0 known binders and
97 disease associations.
Target properties
| Protein name | Zinc finger protein 831 |
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| UniProt accession | Q5JPB2 |
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| Gene | ZNF831 |
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| Organism | Homo sapiens |
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| Length | 1677 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (97)
Diseases linked to this target (Open Targets).
- systolic blood pressure · score 0.46
- diastolic blood pressure · score 0.46
- lymphocyte count · score 0.44
- mean arterial pressure · score 0.44
- hypertension · score 0.44
- lymphocyte percentage of leukocytes · score 0.44
- alcohol drinking · score 0.42
- blood pressure · score 0.41
- hair color · score 0.41
- neutrophil percentage of leukocytes · score 0.41
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5JPB2-F1 | alphafold | PREDICTED | 37.79 | — |
Amino-acid sequence (1677 residues)
MEVPEPTCPA PPARDQPAPT PGPPGAPGGQ ASPHLTLGPV LLPPEQGLAP PTVFLKALPI PLYHTVPPGG LQPRAPLVTG SLDGGNVPFI LSPVLQPEGP GPTQVGKPAA PTLTVNIVGT LPVLSPGLGP TLGSPGKVRN AGKYLCPHCG RDCLKPSVLE KHIRSHTGER PFPCATCGIA FKTQSNLYKH RRTQTHLNNS RLSSESEGAG GGLLEEGDKA GEPPRPEGRG ESRCQGMHEG ASERPLSPGA HVPLLAKNLD VRTEAAPCPG SAFADREAPW DSAPMASPGL PAASTQPWRK LPEQKSPTAG KPCALQRQQA TAAEKPWDAK APEGRLRKCE STDSGYLSRS DSAEQPHAPC SPLHSLSEHS AESEGEGGPG PGPGVAGAEP GAREAGLELE KKRLEERIAQ LISHNQAVVD DAQLDNVRPR KTGLSKQGSI DLPTPYTYKD SFHFDIRALE PGRRRAPGPV RSTWTPPDKS RPLFFHSVPT QLSTTVECVP VTRSNSLPFV EGSRTWLEPR EPRDPWSRTQ KPLSPRPGPA RLGCRSGLSS TDVPSGHPRA LVRQAAVEDL PGTPIGDALV PAEDTDAKRT AAREAMAGKG RAGGRKCGQR RLKMFSQEKW QVYGDETFKR IYQKMKASPH GGKKAREVGM GSGAELGFPL QKEAAGSSGT VPTQDRRTPV HEDISAGATP EPWGNPPALE ASLVTEPTKH GETVARRGDS DRPRVEEAVS SPALGGRDSP CSGSRSPLVS PNGRLELGWQ MPPAPGPLKG GDVEAPRPVW PDPKLEGGAR GVGDVQETCL WAQTVLRWPS RGSGEDKLPS ERKKLKVEDL HSWKQPEPVS AETPGGPTQP ASLSSQKQDA DPGEVPGGSK ESARQVGEPL ESSGASLAAA SVALKRVGPR DKATPLHPAA PAPAEHPSLA TPPQAPRVLS ALADNAFSPK YLLRLPQAET PLPLPIPWGP RHSQDSLCSS GWPEERASFV GSGLGTPLSP SPASGPSPGE ADSILEDPSC SRPQDGRKGA QLGGDKGDRM ATSRPAAREL PISAPGAPRE ATSSPPTPTC EAHLVQDMEG DSHRIHRLCM GSTLARARLS GDVLNPWVPN WELGEPPGNA PEDPSSGPLV GPDPCSPLQP GSFLTALTRP QGVPPGWPEL ALSSHSGTSR SHSTRSPHST QNPFPSLKAE PRLTWCCLSR SVPLPAEQKA KAASVYLAVH FPGSSLRDEG PNGPPGSNGG WTWTSPGEGG PAQMSKFSYP TVPGVMPQHQ VSEPEWKKGL PWRAKMSRGN SKQRKLKINP KRYKGNFLQS CVQLRASRLR TPTWVRRRSR HPPALEGLKP CRTPGQTSSE IAGLNLQEEP SCATSESPPC CGKEEKKEGD CRQTLGTLSL GTSSRIVREM DKRTVKDISP SAGEHGDCTT HSTAATSGLS LQSDTCLAVV NDVPLPPGKG LDLGLLETQL LASQDSVSTD PKPYIFSDAQ RPSSFGSKGT FPHHDIATSV AAVCISLPVR TDHIAQEIHS AESRDHSQTA GRTLTSSSPD SKVTEEGRAQ TLLPGRPSSG QRISDSVPLE STEKTHLEIP ASGPSSASSH HKEGRHKTFF PSRGQYGCGE MTVPCPSLGS DGRKRQVSGL ITRKDSVVPS KPEQPIEIPE APSKSLKKRS LEGMRKQTRV EFSDTSSDDE DRLVIEI
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