About EEF1A lysine methyltransferase 2
EEF1A lysine methyltransferase 2 (EEF1AKMT2) is a protein
from Homo sapiens identified by UniProt accession
Q5JPI9, 236 residues long.
MolForge cross-references it against 0 known binders and
129 disease associations.
Target properties
| Protein name | EEF1A lysine methyltransferase 2 |
|---|
| UniProt accession | Q5JPI9 |
|---|
| Gene | EEF1AKMT2 |
|---|
| Organism | Homo sapiens |
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| Length | 236 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (129)
Diseases linked to this target (Open Targets).
- cortical surface area measurement · score 0.25
- neuroimaging measurement · score 0.25
- glomerular filtration rate · score 0.24
- brain volume measurement · score 0.23
- mean platelet volume · score 0.23
- blood protein measurement · score 0.23
- self reported educational attainment · score 0.22
- heel bone mineral density · score 0.22
- body fat percentage · score 0.22
- fat body mass · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5JPI9-F1 | alphafold | PREDICTED | 89.82 | — |
Amino-acid sequence (236 residues)
MSSGADGGGG AAVAARSDKG SPGEDGFVPS ALGTREHWDA VYERELQTFR EYGDTGEIWF GEESMNRLIR WMQKHKIPLD ASVLDIGTGN GVFLVELAKF GFSNITGIDY SPSAIQLSGS IIEKEGLSNI KLKVEDFLNL STQLSGFHIC IDKGTFDAIS LNPDNAIEKR KQYVKSLSRV LKVKGFFLIT SCNWTKEELL NEFSEGFELL EELPTPKFSF GGRSGNSVAA LVFQKM
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