Uncharacterized protein CXorf66 (CXorf66)

About Uncharacterized protein CXorf66

Uncharacterized protein CXorf66 (CXorf66) is a protein from Homo sapiens identified by UniProt accession Q5JRM2, 361 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Uncharacterized protein CXorf66
UniProt accession	Q5JRM2
Gene	CXorf66
Organism	Homo sapiens
Length	361 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

colorectal adenocarcinoma · score 0.04
non-small cell lung carcinoma · score 0.03
body height · score 0.03
age at onset · score 0.03
Myopia · score 0.03
carcinoma of liver and intrahepatic biliary tract · score 0.02
glioblastoma multiforme · score 0.02
cancer · score 0.01
brain cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5JRM2-F1	alphafold	PREDICTED	53.73	—

Amino-acid sequence (361 residues)

MNLVICVLLL SIWKNNCMTT NQTNGSSTTG DKPVESMQTK LNYLRRNLLI LVGIIIMVFV FICFCYLHYN CLSDDASKAG MVKKKGIAAK SSKTSFSEAK TASQCSPETQ PMLSTADKSS DSSSPERASA QSSTEKLIRP SSLQKPSIPN SAGKLTRPSY PKRSSKSSCS KKLSKSSHLE KAHKKGSLEK LCKLDYACKL ASSDKPVRPP QLFKPLYSSH PQNEISPSKP FGPQELAKPP KHFNPKRSVS LGRAALLSNS ELAETCQPYK KKHLVAKTYR PLVNDISEAK EKNTQNLHVS SKVKSSSRSF RKLDSRNNAY GDHVNDSDTM KYYSEVDSDK VIIITCDRGY NQVTSEVTLN D

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards