Proteasome assembly chaperone 4 (PSMG4)

About Proteasome assembly chaperone 4

Proteasome assembly chaperone 4 (PSMG4) is a protein from Homo sapiens identified by UniProt accession Q5JS54, 123 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Proteasome assembly chaperone 4
UniProt accession	Q5JS54
Gene	PSMG4
Organism	Homo sapiens
Length	123 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
electrocardiography · score 0.41
mean platelet volume · score 0.28
medical procedure · score 0.24
Red cell distribution width · score 0.04
lung adenocarcinoma · score 0.04
PHF-tau measurement · score 0.04
metabolite measurement · score 0.03
neoplasm · score 0.01
ovarian carcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5JS54-F1	alphafold	PREDICTED	87.03	—

Amino-acid sequence (123 residues)

MEGLVVAAGG DVSLHNFSAR LWEQLVHFHV MRLTDSLFLW VGATPHLRNL AVAMCSRYDS IPVSTSLLGD TSDTTSTGLA QRLARKTNKQ VFVSYNLQNT DSNFALLVEN RIKEEMEAFP EKF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards