KHDC1-like protein (KHDC1L)

About KHDC1-like protein

KHDC1-like protein (KHDC1L) is a protein from Homo sapiens identified by UniProt accession Q5JSQ8, 128 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	KHDC1-like protein
UniProt accession	Q5JSQ8
Gene	KHDC1L
Organism	Homo sapiens
Length	128 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

body mass index · score 0.19
primary ovarian insufficiency · score 0.12
head and neck squamous cell carcinoma · score 0.07
refractive error · score 0.04
body weight · score 0.04
snoring measurement · score 0.04
FEV/FVC ratio · score 0.04
Myopia · score 0.04
refractive error measurement · score 0.04
pulse pressure measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5JSQ8-F1	alphafold	PREDICTED	87.73	—

Amino-acid sequence (128 residues)

MAVGTSALSK EPWWTLPENF HSPMVFHMEE DQEELIFGLD DTYLRCIELH SHTLIQLERC FTATGQTRVT VVGPPMAKQW LLLMFHCVGS QDSKCHARGL KMLERVRSQP LTNDDLVTSV SLPPYTGD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards