About Zinc finger protein 569
Zinc finger protein 569 (ZNF569) is a protein
from Homo sapiens identified by UniProt accession
Q5MCW4, 686 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Zinc finger protein 569 |
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| UniProt accession | Q5MCW4 |
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| Gene | ZNF569 |
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| Organism | Homo sapiens |
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| Length | 686 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (21)
Diseases linked to this target (Open Targets).
- head and neck squamous cell carcinoma · score 0.07
- hematocrit · score 0.06
- Zinc deficiency · score 0.05
- deafness · score 0.05
- sex hormone-binding globulin measurement · score 0.05
- body height · score 0.04
- hypertension · score 0.03
- neoplasm · score 0.03
- C-reactive protein measurement · score 0.03
- infection · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5MCW4-F1 | alphafold | PREDICTED | 75.87 | — |
Amino-acid sequence (686 residues)
MTESQGTVTF KDVAIDFTQE EWKRLDPAQR KLYRNVMLEN YNNLITVGYP FTKPDVIFKL EQEEEPWVME EEVLRRHWQG EIWGVDEHQK NQDRLLRQVE VKFQKTLTEE KGNECQKKFA NVFPLNSDFF PSRHNLYEYD LFGKCLEHNF DCHNNVKCLM RKEHCEYNEP VKSYGNSSSH FVITPFKCNH CGKGFNQTLD LIRHLRIHTG EKPYECSNCR KAFSHKEKLI KHYKIHSREQ SYKCNECGKA FIKMSNLIRH QRIHTGEKPY ACKECEKSFS QKSNLIDHEK IHTGEKPYEC NECGKAFSQK QSLIAHQKVH TGEKPYACNE CGKAFPRIAS LALHMRSHTG EKPYKCDKCG KAFSQFSMLI IHVRIHTGEK PYECNECGKA FSQSSALTVH MRSHTGEKPY ECKECRKAFS HKKNFITHQK IHTREKPYEC NECGKAFIQM SNLVRHQRIH TGEKPYICKE CGKAFSQKSN LIAHEKIHSG EKPYECNECG KAFSQKQNFI THQKVHTGEK PYDCNECGKA FSQIASLTLH LRSHTGEKPY ECDKCGKAFS QCSLLNLHMR SHTGEKPYVC NECGKAFSQR TSLIVHMRGH TGEKPYECNK CGKAFSQSSS LTIHIRGHTG EKPFDCSKCG KAFSQISSLT LHMRKHTGEK PYHCIECGKA FSQKSHLVRH QRIHTH
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