Sodium/bile acid cotransporter 5 (SLC10A5)

About Sodium/bile acid cotransporter 5

Sodium/bile acid cotransporter 5 (SLC10A5) is a protein from Homo sapiens identified by UniProt accession Q5PT55, 438 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Sodium/bile acid cotransporter 5
UniProt accession	Q5PT55
Gene	SLC10A5
Organism	Homo sapiens
Length	438 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

reticulocyte count · score 0.16
platelet crit · score 0.15
platelet count · score 0.09
ovarian carcinoma · score 0.03
mean platelet volume · score 0.03
ovarian serous carcinoma · score 0.02
age-related hearing impairment · score 0.02
cystatin C measurement · score 0.02
blood phosphate measurement · score 0.02
malignant epithelial tumor of ovary · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5PT55-F1	alphafold	PREDICTED	80.21	—

Amino-acid sequence (438 residues)

MIRKLFIVLL LLLVTIEEAR MSSLSFLNIE KTEILFFTKT EETILVSSSY ENKRPNSSHL FVKIEDPKIL QMVNVAKKIS SDATNFTINL VTDEEGETNV TIQLWDSEGR QERLIEEIKN VKVKVLKQKD SLLQAPMHID RNILMLILPL ILLNKCAFGC KIELQLFQTV WKRPLPVILG AVTQFFLMPF CGFLLSQIVA LPEAQAFGVV MTCTCPGGGG GYLFALLLDG DFTLAILMTC TSTLLALIMM PVNSYIYSRI LGLSGTFHIP VSKIVSTLLF ILVPVSIGIV IKHRIPEKAS FLERIIRPLS FILMFVGIYL TFTVGLVFLK TDNLEVILLG LLVPALGLLF GYSFAKVCTL PLPVCKTVAI ESGMLNSFLA LAVIQLSFPQ SKANLASVAP FTVAMCSGCE MLLIILVYKA KKRCIFFLQD KRKRNFLI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards