About Cytochrome c oxidase assembly protein COX20, mitochondrial
Cytochrome c oxidase assembly protein COX20, mitochondrial (COX20) is a protein
from Homo sapiens identified by UniProt accession
Q5RI15, 118 residues long.
MolForge cross-references it against 0 known binders and
48 disease associations.
Target properties
| Protein name | Cytochrome c oxidase assembly protein COX20, mitochondrial |
|---|
| UniProt accession | Q5RI15 |
|---|
| Gene | COX20 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 118 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (48)
Diseases linked to this target (Open Targets).
- mitochondrial complex 4 deficiency, nuclear type 11 · score 0.71
- cytochrome-c oxidase deficiency disease · score 0.57
- mitochondrial disease · score 0.40
- genetic disorder · score 0.39
- Isolated cytochrome C oxidase deficiency · score 0.37
- viral load · score 0.17
- mitochondrial complex IV deficiency, nuclear type 22 · score 0.15
- leigh syndrome due to mitochondrial complex iv deficiency · score 0.15
- gastric adenocarcinoma · score 0.14
- urinary bladder cancer · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5RI15-F1 | alphafold | PREDICTED | 65.90 | — |
Amino-acid sequence (118 residues)
MAAPPEPGEP EERKSLKLLG FLDVENTPCA RHSILYGSLG SVVAGFGHFL FTSRIRRSCD VGVGGFILVT LGCWFHCRYN YAKQRIQERI AREEIKKKIL YEGTHLDPER KHNGSSSN
Explore Cytochrome c oxidase assembly protein COX20, mitochondrial with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets