About Phytanoyl-CoA dioxygenase domain-containing protein 1
Phytanoyl-CoA dioxygenase domain-containing protein 1 (PHYHD1) is a protein
from Homo sapiens identified by UniProt accession
Q5SRE7, 291 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | Phytanoyl-CoA dioxygenase domain-containing protein 1 |
|---|
| UniProt accession | Q5SRE7 |
|---|
| Gene | PHYHD1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 291 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- serum metabolite measurement · score 0.32
- urinary metabolite measurement · score 0.29
- metabolite measurement · score 0.22
- body height · score 0.04
- chronotype measurement · score 0.04
- clear cell renal carcinoma · score 0.03
- laryngeal squamous cell carcinoma · score 0.03
- gastric carcinoma · score 0.02
- erythrocyte count · score 0.02
- hemoglobin measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5SRE7-F1 | alphafold | PREDICTED | 93.46 | — |
Amino-acid sequence (291 residues)
MACLSPSQLQ KFQQDGFLVL EGFLSAEECV AMQQRIGEIV AEMDVPLHCR TEFSTQEEEQ LRAQGSTDYF LSSGDKIRFF FEKGVFDEKG NFLVPPEKSI NKIGHALHAH DPVFKSITHS FKVQTLARSL GLQMPVVVQS MYIFKQPHFG GEVSPHQDAS FLYTEPLGRV LGVWIAVEDA TLENGCLWFI PGSHTSGVSR RMVRAPVGSA PGTSFLGSEP ARDNSLFVPT PVQRGALVLI HGEVVHKSKQ NLSDRSRQAY TFHLMEASGT TWSPENWLQP TAELPFPQLY T
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