About Mucin-21
Mucin-21 (MUC21) is a protein
from Homo sapiens identified by UniProt accession
Q5SSG8, 566 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Mucin-21 |
|---|
| UniProt accession | Q5SSG8 |
|---|
| Gene | MUC21 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 566 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (68)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.29
- lung adenocarcinoma · score 0.27
- squamous cell lung carcinoma · score 0.27
- breast adenocarcinoma · score 0.26
- thyroid gland adenocarcinoma · score 0.22
- head and neck squamous cell carcinoma · score 0.22
- complement C4 measurement · score 0.19
- Takayasu arteritis · score 0.18
- gastric adenocarcinoma · score 0.17
- cutaneous lupus erythematosus · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5SSG8-F1 | alphafold | PREDICTED | 75.52 | — |
Amino-acid sequence (566 residues)
MKMQKGNVLL MFGLLLHLEA ATNSNETSTS ANTGSSVISS GASTATNSGS SVTSSGVSTA TISGSSVTSN GVSIVTNSEF HTTSSGISTA TNSEFSTVSS GISIATNSES STTSSGASTA TNSESSTPSS GASTATNSDS STTSSGASTA TNSDSSTTSS EASTATNSES STTSSGASTA TNSESSTVSS RASTATNSES STTSSGASTA TNSESRTTSN GAGTATNSES STTSSGASTA TNSESSTPSS GAGTATNSES STTSSGAGTA TNSESSTVSS GISTVTNSES STPSSGANTA TNSESSTTSS GANTATNSDS STTSSGASTA TNSESSTTSS GASTATNSES STTSSGASTA TNSGSSTTSS GTSTATNSES STVSSGASTA TTSESSTTSS GASTATNSES STVSSGASTA TNSESSTTSS GANTATNSGS SVTSAGSGTA ALTGMHTTSH SASTAVSEAK PGGSLVPWEI FLITLVSVVA AVGLFAGLFF CVRNSLSLRN TFNTAVYHPH GLNHGLGPGP GGNHGAPHRP RWSPNWFWRR PVSSIAMEMS GRNSGP
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