About Heterochromatin protein 1-binding protein 3
Heterochromatin protein 1-binding protein 3 (HP1BP3) is a protein
from Homo sapiens identified by UniProt accession
Q5SSJ5, 553 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | Heterochromatin protein 1-binding protein 3 |
|---|
| UniProt accession | Q5SSJ5 |
|---|
| Gene | HP1BP3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 553 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (53)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- body height · score 0.26
- chronotype measurement · score 0.10
- wellbeing measurement · score 0.10
- insulin like growth factor measurement · score 0.09
- depressive symptom measurement · score 0.09
- neuroticism measurement · score 0.09
- cortical thickness · score 0.09
- risk-taking behaviour · score 0.09
- hematocrit · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5SSJ5-F1 | alphafold | PREDICTED | 65.29 | — |
Amino-acid sequence (553 residues)
MATDTSQGEL VHPKALPLIV GAQLIHADKL GEKVEDSTMP IRRTVNSTRE TPPKSKLAEG EEEKPEPDIS SEESVSTVEE QENETPPATS SEAEQPKGEP ENEEKEENKS SEETKKDEKD QSKEKEKKVK KTIPSWATLS ASQLARAQKQ TPMASSPRPK MDAILTEAIK ACFQKSGASV VAIRKYIIHK YPSLELERRG YLLKQALKRE LNRGVIKQVK GKGASGSFVV VQKSRKTPQK SRNRKNRSSA VDPEPQVKLE DVLPLAFTRL CEPKEASYSL IRKYVSQYYP KLRVDIRPQL LKNALQRAVE RGQLEQITGK GASGTFQLKK SGEKPLLGGS LMEYAILSAI AAMNEPKTCS TTALKKYVLE NHPGTNSNYQ MHLLKKTLQK CEKNGWMEQI SGKGFSGTFQ LCFPYYPSPG VLFPKKEPDD SRDEDEDEDE SSEEDSEDEE PPPKRRLQKK TPAKSPGKAA SVKQRGSKPA PKVSAAQRGK ARPLPKKAPP KAKTPAKKTR PSSTVIKKPS GGSSKKPATS ARKEVKLPGK GKSTMKKSFR VKK
Explore Heterochromatin protein 1-binding protein 3 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets