About Kidney mitochondrial carrier protein 1
Kidney mitochondrial carrier protein 1 (SLC25A30) is a protein
from Homo sapiens identified by UniProt accession
Q5SVS4, 291 residues long.
MolForge cross-references it against 0 known binders and
20 disease associations.
Target properties
| Protein name | Kidney mitochondrial carrier protein 1 |
|---|
| UniProt accession | Q5SVS4 |
|---|
| Gene | SLC25A30 |
|---|
| Organism | Homo sapiens |
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| Length | 291 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (20)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.46
- triglyceride measurement · score 0.30
- urate measurement · score 0.28
- type 1 diabetes mellitus · score 0.15
- alkaline phosphatase measurement · score 0.13
- alanine measurement · score 0.12
- acute quadriplegic myopathy · score 0.01
- hepatocellular carcinoma · score 0.01
- perivascular space measurement · score 0.00
- infect · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5SVS4-F1 | alphafold | PREDICTED | 80.43 | — |
Amino-acid sequence (291 residues)
MSALNWKPFV YGGLASITAE CGTFPIDLTK TRLQIQGQTN DAKFKEIRYR GMLHALVRIG REEGLKALYS GIAPAMLRQA SYGTIKIGTY QSLKRLFIER PEDETLPINV ICGILSGVIS STIANPTDVL KIRMQAQSNT IQGGMIGNFM NIYQQEGTRG LWKGVSLTAQ RAAIVVGVEL PVYDITKKHL ILSGLMGDTV YTHFLSSFTC GLAGALASNP VDVVRTRMMN QRVLRDGRCS GYTGTLDCLL QTWKNEGFFA LYKGFWPNWL RLGPWNIIFF VTYEQLKKLD L
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