About Clavesin-2
Clavesin-2 (CLVS2) is a protein
from Homo sapiens identified by UniProt accession
Q5SYC1, 327 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Clavesin-2 |
|---|
| UniProt accession | Q5SYC1 |
|---|
| Gene | CLVS2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 327 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (12)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.31
- Abnormality of refraction · score 0.31
- alcohol drinking · score 0.26
- incomplete abortion · score 0.07
- Ataxia-telangiectasia · score 0.02
- colorectal cancer · score 0.02
- prostate adenocarcinoma · score 0.01
- endometrial carcinoma · score 0.00
- Crohn's disease · score 0.00
- pachyonychia congenita · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5SYC1-F1 | alphafold | PREDICTED | 85.91 | — |
Amino-acid sequence (327 residues)
MTHLQAGLSP ETLEKARLEL NENPDTLHQD IQEVRDMVIT RPDIGFLRTD DAFILRFLRA RKFHHFEAFR LLAQYFEYRQ QNLDMFKSFK ATDPGIKQAL KDGFPGGLAN LDHYGRKILV LFAANWDQSR YTLVDILRAI LLSLEAMIED PELQVNGFVL IIDWSNFTFK QASKLTPSML RLAIEGLQDS FPARFGGIHF VNQPWYIHAL YTVIRPFLKE KTRKRIFLHG NNLNSLHQLI HPEILPSEFG GMLPPYDMGT WARTLLDHEY DDDSEYNVDS YSMPVKEVEK ELSPKSMKRS QSVVDPTVLK RMDKNEEENM QPLLSLD
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