About Arginine vasopressin-induced protein 1
Arginine vasopressin-induced protein 1 (AVPI1) is a protein
from Homo sapiens identified by UniProt accession
Q5T686, 147 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | Arginine vasopressin-induced protein 1 |
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| UniProt accession | Q5T686 |
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| Gene | AVPI1 |
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| Organism | Homo sapiens |
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| Length | 147 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (38)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.27
- alcohol dependence · score 0.07
- risky sexual behaviour measurement · score 0.07
- Familial short QT syndrome · score 0.05
- sinoatrial node dysfunction and deafness · score 0.05
- familial atrial fibrillation · score 0.05
- catecholaminergic polymorphic ventricular tachycardia 1 · score 0.04
- ventricular fibrillation, paroxysmal familial, type 1 · score 0.04
- long QT syndrome 5 · score 0.04
- Brugada syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5T686-F1 | alphafold | PREDICTED | 70.97 | — |
Amino-acid sequence (147 residues)
MGTPASVVSE PPPWQAPIEA RGRKQASANI FQDAELLQIQ ALFQRSGDQL AEERAQIIWE CAGDHRVAEA LKRLRRKRPP RQKPLGHSLH HCSRLRILEP HSALANPQSA TETASSEQYL HSRKKSARIR RNWRKSGPTS YLHQIRH
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