Late cornified envelope protein 1D (LCE1D)

About Late cornified envelope protein 1D

Late cornified envelope protein 1D (LCE1D) is a protein from Homo sapiens identified by UniProt accession Q5T752, 114 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

Target properties

Protein name	Late cornified envelope protein 1D
UniProt accession	Q5T752
Gene	LCE1D
Organism	Homo sapiens
Length	114 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (10)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.32
breast adenocarcinoma · score 0.22
prostate adenocarcinoma · score 0.21
esophageal cancer · score 0.17
endometrial cancer · score 0.10
drug use measurement · score 0.04
atopic eczema · score 0.03
vitamin D measurement · score 0.03
meningeal tuberculosis · score 0.00
chronic kidney disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5T752-F1	alphafold	PREDICTED	52.25	—

Amino-acid sequence (114 residues)

MSCQQSQQQC QPPPKCTPKC TPKCPAPKCP PKCPPVSSCC SVSSGGCCGS SSGGGCGSNS GGCCSSGGGG CCLSHHRRHR SHRRRPQSSD CCSQPSGGSS CCGGGSSQHS GGCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards