About Ceramide-1-phosphate transfer protein
Ceramide-1-phosphate transfer protein (CPTP) is a protein
from Homo sapiens identified by UniProt accession
Q5TA50, 214 residues long.
MolForge cross-references it against 0 known binders and
28 disease associations.
Target properties
| Protein name | Ceramide-1-phosphate transfer protein |
|---|
| UniProt accession | Q5TA50 |
|---|
| Gene | CPTP |
|---|
| Organism | Homo sapiens |
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| Length | 214 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (28)
Diseases linked to this target (Open Targets).
- refractive error measurement · score 0.21
- systolic blood pressure · score 0.11
- pachyonychia congenita · score 0.07
- pulse pressure measurement · score 0.07
- inflammatory bowel disease · score 0.06
- myxedema · score 0.04
- Drugs affecting bone structure and mineralization use measurement · score 0.03
- intraocular pressure measurement · score 0.03
- ulcerative colitis · score 0.03
- neoplasm · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5TA50-F1 | alphafold | PREDICTED | 93.83 | — |
Amino-acid sequence (214 residues)
MDDSETGFNL KVVLVSFKQC LDEKEEVLLD PYIASWKGLV RFLNSLGTIF SFISKDVVSK LRIMERLRGG PQSEHYRSLQ AMVAHELSNR LVDLERRSHH PESGCRTVLR LHRALHWLQL FLEGLRTSPE DARTSALCAD SYNASLAAYH PWVVRRAVTV AFCTLPTREV FLEAMNVGPP EQAVQMLGEA LPFIQRVYNV SQKLYAEHSL LDLP
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