Late cornified envelope protein 2A (LCE2A)

About Late cornified envelope protein 2A

Late cornified envelope protein 2A (LCE2A) is a protein from Homo sapiens identified by UniProt accession Q5TA79, 106 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Late cornified envelope protein 2A
UniProt accession	Q5TA79
Gene	LCE2A
Organism	Homo sapiens
Length	106 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.22
gastric adenocarcinoma · score 0.16
psoriasis · score 0.02
COVID-19 · score 0.02
diabetes mellitus · score 0.00
van der Woude syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5TA79-F1	alphafold	PREDICTED	53.45	—

Amino-acid sequence (106 residues)

MSCQQNQQQC QPPPKCPPKC PPKCPPKCRP QCPAPCPPPV SSCCGPSSGG CCGSSSGGCC SSGGGGCCLS HHRPRLFHRH RHQSPDCCEC EPSGGSGCCH SSGDCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards