Late cornified envelope protein 5A (LCE5A)

About Late cornified envelope protein 5A

Late cornified envelope protein 5A (LCE5A) is a protein from Homo sapiens identified by UniProt accession Q5TCM9, 118 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

Target properties

Protein name	Late cornified envelope protein 5A
UniProt accession	Q5TCM9
Gene	LCE5A
Organism	Homo sapiens
Length	118 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (18)

Diseases linked to this target (Open Targets).

atopic eczema · score 0.26
glioblastoma multiforme · score 0.23
prostate adenocarcinoma · score 0.21
ovarian cancer · score 0.18
childhood onset asthma · score 0.17
atopic march · score 0.17
gastric adenocarcinoma · score 0.16
hair morphology · score 0.15
susceptibility to plantar warts measurement · score 0.15
low grade glioma · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5TCM9-F1	alphafold	PREDICTED	52.45	—

Amino-acid sequence (118 residues)

MSCQQSQQQC QPPPKCTPKC PPKCTPKCPP KCPPKCPPQC SAPCPPPVSS CCGSSSGGCC SSEGGGCCLS HHRPRQSLRR RPQSSSCCGS GSGQQSGGSS CCHSSGGSGC CHSSGGCC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards