About Lengsin
Lengsin (LGSN) is a protein
from Homo sapiens identified by UniProt accession
Q5TDP6, 509 residues long.
MolForge cross-references it against 0 known binders and
40 disease associations.
Target properties
| Protein name | Lengsin |
|---|
| UniProt accession | Q5TDP6 |
|---|
| Gene | LGSN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 509 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (40)
Diseases linked to this target (Open Targets).
- body mass index · score 0.05
- gonorrhea · score 0.05
- non-small cell lung carcinoma · score 0.04
- asthma · score 0.04
- neoplasm · score 0.04
- pancreatic adenocarcinoma · score 0.04
- DNA methylation · score 0.03
- cancer · score 0.03
- type 2 diabetes mellitus · score 0.03
- respiratory system disease · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5TDP6-F1 | alphafold | PREDICTED | 77.47 | — |
Amino-acid sequence (509 residues)
MNNEEDLLQE DSTRDEGNET EANSMNTLRR TRKKVTKPYV CSTEVGETDM SNSNDCMRDS SQILTPPQLS SRMKHIRQAM AKNRLQFVRF EATDLHGVSR SKTIPAHFFQ EKVSHGVCMP RGYLEVIPNP KDNEMNNIRA TCFNSDIVLM PELSTFRVLP WADRTARVIC DTFTVTGEPL LTSPRYIAKR QLSHLQASGF SLLSAFIYDF CIFGVPEILN SKIISFPALT FLNNHDQPFM QELVDGLYHT GANVESFSSS TRPGQMEISF LPEFGISSAD NAFTLRTGVK EVARKYNYIA SFFIETGFCD SGILSHSLWD VDRKKNMFCS TSGTEQLTIT GKKWLAGLLK HSAALSCLMA PSVSCRKRYS KDRKDLKKSV PTTWGYNDNS CIFNIKCHGE KGTRIENKLG SATANPYLVL AATVAAGLDG LHSSNEVLAG PDESTDFYQV EPSEIPLKLE DALVALEEDQ CLRQALGETF IRYFVAMKKY ELENEEIAAE RNKFLEYFI
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