Solute carrier family 60 member 1 (SLC60A2)

About Solute carrier family 60 member 1

Solute carrier family 60 member 1 (SLC60A2) is a protein from Homo sapiens identified by UniProt accession Q5TF39, 518 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

Target properties

Protein name	Solute carrier family 60 member 1
UniProt accession	Q5TF39
Gene	SLC60A2
Organism	Homo sapiens
Length	518 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (54)

Diseases linked to this target (Open Targets).

psoriasis · score 0.43
smoking initiation · score 0.37
serum metabolite measurement · score 0.34
erythrocyte count · score 0.32
smoking status measurement · score 0.32
Red cell distribution width · score 0.29
age at menopause · score 0.24
urate measurement · score 0.22
mean corpuscular volume · score 0.21
type 2 diabetes mellitus · score 0.20

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5TF39-F1	alphafold	PREDICTED	78.40	—

Amino-acid sequence (518 residues)

MLCASFLGLG LSVAIVGPTF QDLATNVNRN ISSLSFIFVG RALGYLSGSV IGGFLVDVMN YFLLLGISMS ATTVGLYLVP FCKTAILLTV MMSIFGVSIG ILDTGGNVLI LAIWGDKGAP HMQALHFSFA LGAFLAPLLA KLALGPTASA ENHTESDFHP ALNQSSDADS EALFGVPNDK NLLWAYAVIG TYMFLVSVIF FCLFLKNSSK QEKARASAET FRRAKYHNAL LCLLFLFFFF YVGAEVTYGS YVFSFATTHA GMKESEAAGL NSIFWGTFAA CRGLAIFFAT CLQPGTMIVL SNIGSLTSSL FLVLFDKNPI CLWIATSVYG ASMATTFPSG VSWIEQYTTI HGKSAAFFVI GASLGEMAIP AVIGILQGKY PDLPVVLYTS LGASIATGIL FPVLYKLATS PLDRQRKEDR KSEDQKALLS SSGLNEYEEE NEEEDAEKWN EMDFEMIETN DTMRHSIIET SRSSLTEPTA EVYNQYPSNA LVFESSPFNT GSAHVKHLPE TRTKGTNV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards