About Protein FAM78B
Protein FAM78B (FAM78B) is a protein
from Homo sapiens identified by UniProt accession
Q5VT40, 261 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Protein FAM78B |
|---|
| UniProt accession | Q5VT40 |
|---|
| Gene | FAM78B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 261 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.42
- cortical thickness · score 0.40
- self reported educational attainment · score 0.38
- leukocyte count · score 0.32
- neutrophil count · score 0.32
- cocaine dependence · score 0.31
- risk-taking behaviour · score 0.25
- lymphocyte count · score 0.08
- pancreatic adenocarcinoma · score 0.03
- atypical teratoid rhabdoid tumor · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5VT40-F1 | alphafold | PREDICTED | 94.74 | — |
Amino-acid sequence (261 residues)
MGCIQSITCK ARIRRENIVV YDVCATIDQC PTRIEETSPI VLRYKTPYFK ASARVVMPPI PRHETWVVGW IQACNQMEFF NTYSDLGMSS WELPDLREGR VKAISDSDGV SYPWYGNTTE TVTLVGPTNK ISRFSVSMND NFYPSVTWAV PVSDSNVPLL TRIKRDQSFT TWLVAMNTTT KEKIILQTIK WRMRVDIEVD PLQLLGQRAR LVGRTQQEQP RILSRMEPIP PNALVKPNAN DAQVLMWRPK RGPPLVVIPP K
Explore Protein FAM78B with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets