Mitochondrial amidoxime-reducing component 1 (MTARC1)

About Mitochondrial amidoxime-reducing component 1

Mitochondrial amidoxime-reducing component 1 (MTARC1) is a protein from Homo sapiens identified by UniProt accession Q5VT66, 337 residues long. MolForge cross-references it against 0 known binders and 137 disease associations.

Target properties

Protein name	Mitochondrial amidoxime-reducing component 1
UniProt accession	Q5VT66
Gene	MTARC1
Organism	Homo sapiens
Length	337 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (137)

Diseases linked to this target (Open Targets).

low density lipoprotein cholesterol measurement · score 0.49
high density lipoprotein cholesterol measurement · score 0.49
total cholesterol measurement · score 0.48
vitamin D measurement · score 0.47
alkaline phosphatase measurement · score 0.47
serum alanine aminotransferase measurement · score 0.47
sex hormone-binding globulin measurement · score 0.46
triglyceride measurement · score 0.46
alcohol consumption measurement · score 0.45
alcohol drinking · score 0.45

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VT66-F1	alphafold	PREDICTED	91.29	—

Amino-acid sequence (337 residues)

MGAAGSSALA RFVLLAQSRP GWLGVAALGL TAVALGAVAW RRAWPTRRRR LLQQVGTVAQ LWIYPVKSCK GVPVSEAECT AMGLRSGNLR DRFWLVINQE GNMVTARQEP RLVLISLTCD GDTLTLSAAY TKDLLLPIKT PTTNAVHKCR VHGLEIEGRD CGEATAQWIT SFLKSQPYRL VHFEPHMRPR RPHQIADLFR PKDQIAYSDT SPFLILSEAS LADLNSRLEK KVKATNFRPN IVISGCDVYA EDSWDELLIG DVELKRVMAC SRCILTTVDP DTGVMSRKEP LETLKSYRQC DPSERKLYGK SPLFGQYFVL ENPGTIKVGD PVYLLGQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards