Annexin A8-like protein 1 (ANXA8L1)

About Annexin A8-like protein 1

Annexin A8-like protein 1 (ANXA8L1) is a protein from Homo sapiens identified by UniProt accession Q5VT79, 327 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Annexin A8-like protein 1
UniProt accession	Q5VT79
Gene	ANXA8L1
Organism	Homo sapiens
Length	327 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

benign neoplasm · score 0.08
mean corpuscular volume · score 0.07
mean corpuscular hemoglobin · score 0.07
mean corpuscular hemoglobin concentration · score 0.06
erythrocyte count · score 0.06
red blood cell density measurement · score 0.06
prostate carcinoma · score 0.04
esophageal adenocarcinoma · score 0.03
renal cell carcinoma · score 0.02
gastric adenocarcinoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VT79-F1	alphafold	PREDICTED	94.24	—

Amino-acid sequence (327 residues)

MAWWKAWIEQ EGVTVKSSSH FNPDPDAETL YKAMKGIGTN EQAIIDVLTK RSNTQRQQIA KSFKAQFGKD LTETLKSELS GKFERLIVAL MYPPYRYEAK ELHDAMKGLG TKEGVIIEIL ASRTKNQLRE IMKAYEEDYG SSLEEDIQAD TSGYLERILV CLLQGSRDDV SSFVDPALAL QDAQDLYAAG EKIRGTDEMK FITILCTRSA THLLRVFEEY EKIANKSIED SIKSETHGSL EEAMLTVVKC TQNLHSYFAE RLYYAMKGAG TRDGTLIRNI VSRSEIDLNL IKCHFKKMYG KTLSSMIMED TSGDYKNALL SLVGSDP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards