Protein Flattop (CFAP126)

About Protein Flattop

Protein Flattop (CFAP126) is a protein from Homo sapiens identified by UniProt accession Q5VTH2, 177 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.

Target properties

Protein name	Protein Flattop
UniProt accession	Q5VTH2
Gene	CFAP126
Organism	Homo sapiens
Length	177 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (17)

Diseases linked to this target (Open Targets).

hereditary pheochromocytoma-paraganglioma · score 0.40
adrenal gland pheochromocytoma · score 0.19
ependymoma · score 0.04
nasopharyngeal neoplasm · score 0.01
fleck corneal dystrophy · score 0.01
type 2 diabetes mellitus · score 0.01
prediabetes syndrome · score 0.01
small cell lung carcinoma · score 0.00
neoplasm · score 0.00
Anorexia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VTH2-F1	alphafold	PREDICTED	72.63	—

Amino-acid sequence (177 residues)

MATNYSANQY EKAFSSKYLQ NWSPTKPTKE SISSHEGYTQ IIANDRGHLL PSVPRSKANP WGSFMGTWQM PLKIPPARVT LTSRTTAGAA SLTKWIQKNP DLLKASNGLC PEILGKPHDP DSQKKLRKKS ITKTVQQARS PTIIPSSPAA NLNSPDELQS SHPSAGHTPG PQRPAKS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards