Cilia- and flagella-associated protein 95 (CFAP95)

About Cilia- and flagella-associated protein 95

Cilia- and flagella-associated protein 95 (CFAP95) is a protein from Homo sapiens identified by UniProt accession Q5VTT2, 229 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Cilia- and flagella-associated protein 95
UniProt accession	Q5VTT2
Gene	CFAP95
Organism	Homo sapiens
Length	229 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

CD5 measurement · score 0.32
intraocular pressure measurement · score 0.25
bilirubin measurement · score 0.13
mean platelet volume · score 0.10
Red cell distribution width · score 0.10
corneal resistance factor · score 0.03
cognitive function measurement · score 0.03
age at first sexual intercourse measurement · score 0.02
protein measurement · score 0.02
bone density · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VTT2-F1	alphafold	PREDICTED	63.08	—

Amino-acid sequence (229 residues)

MDSLDRSCQD WCDRKQHWLE IGPPDLVERK GSLTLRSHHK KYSKPVLVYS WHRDREAFPK GYDIEGPEKV KKLCNSTYRR LGTDESPIWT SETHEKLSQM CLNTEWVEMK SKALLNEETV SSGIIERVTG LPATGFGAVF PRHPPDWSKM CALTTYSEDY VPPYDYQPHA YPCQDDYSIV HRKCRSQFTD LNGSKRFGIN TWHDESGIYA NSDVKQKLYP LTSGPIVPI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards