About Myomesin-3
Myomesin-3 (MYOM3) is a protein
from Homo sapiens identified by UniProt accession
Q5VTT5, 1437 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Myomesin-3 |
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| UniProt accession | Q5VTT5 |
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| Gene | MYOM3 |
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| Organism | Homo sapiens |
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| Length | 1437 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (30)
Diseases linked to this target (Open Targets).
- Flexion contracture · score 0.11
- Duchenne muscular dystrophy · score 0.07
- lymphocyte count · score 0.06
- appendicular lean mass · score 0.04
- Red cell distribution width · score 0.03
- psychotic symptoms · score 0.02
- autosomal recessive limb-girdle muscular dystrophy type 2D · score 0.02
- Muscular dystrophy · score 0.02
- muscular dystrophy · score 0.02
- Colon Sessile Serrated Adenoma/Polyp · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5VTT5-F1 | alphafold | PREDICTED | 76.27 | — |
Amino-acid sequence (1437 residues)
MTLPHSLGGA GDPRPPQAME VHRLEHRQEE EQKEERQHSL RMGSSVRRRT FRSSEEEHEF SAADYALAAA LALTASSELS WEAQLRRQTS AVELEERGQK RVGFGNDWER TEIAFLQTHR LLRQRRDWKT LRRRTEEKVQ EAKELRELCY GRGPWFWIPL RSHAVWEHTT VLLTCTVQAS PPPQVTWYKN DTRIDPRLFR AGKYRITNNY GLLSLEIRRC AIEDSATYTV RVKNAHGQAS SFAKVLVRTY LGKDAGFDSE IFKRSTFGPS VEFTSVLKPV FAREKEPFSL SCLFSEDVLD AESIQWFRDG SLLRSSRRRK ILYTDRQASL KVSCTYKEDE GLYMVRVPSP FGPREQSTYV LVRDAEAENP GAPGSPLNVR CLDVNRDCLI LTWAPPSDTR GNPITAYTIE RCQGESGEWI ACHEAPGGTC RCPIQGLVEG QSYRFRVRAI SRVGSSVPSK ASELVVMGDH DAARRKTEIP FDLGNKITIS TDAFEDTVTI PSPPTNVHAS EIREAYVVLA WEEPSPRDRA PLTYSLEKSV IGSGTWEAIS SESPVRSPRF AVLDLEKKKS YVFRVRAMNQ YGLSDPSEPS EPIALRGPPA TLPPPAQVQA FRDTQTSVSL TWDPVKDPEL LGYYIYSRKV GTSEWQTVNN KPIQGTRFTV PGLRTGKEYE FCVRSVSEAG VGESSAATEP IRVKQALATP SAPYGFALLN CGKNEMVIGW KPPKRRGGGK ILGYFLDQHD SEELDWHAVN QQPIPTRVCK VSDLHEGHFY EFRARAANWA GVGELSAPSS LFECKEWTMP QPGPPYDVRA SEVRATSLVL QWEPPLYMGA GPVTGYHVSF QEEGSEQWKP VTPGPISGTH LRVSDLQPGK SYVFQVQAMN SAGLGQPSMP TDPVLLEDKP GAHEIEVGVD EEGFIYLAFE APEAPDSSEF QWSKDYKGPL DPQRVKIEDK VNKSKVILKE PGLEDLGTYS VIVTDADEDI SASHTLTEEE LEKLKKLSHE IRNPVIKLIS GWNIDILERG EVRLWLEVEK LSPAAELHLI FNNKEIFSSP NRKINFDREK GLVEVIIQNL SEEDKGSYTA QLQDGKAKNQ ITLTLVDDDF DKLLRKADAK RRDWKRKQGP YFERPLQWKV TEDCQVQLTC KVTNTKKETR FQWFFQRAEM PDGQYDPETG TGLLCIEELS KKDKGIYRAM VSDDRGEDDT ILDLTGDALD AIFTELGRIG ALSATPLKIQ GTEEGIRIFS KVKYYNVEYM KTTWFHKDKR LESGDRIRTG TTLDEIWLHI LDPKDSDKGK YTLEIAAGKE VRQLSTDLSG QAFEDAMAEH QRLKTLAIIE KNRAKVVRGL PDVATIMEDK TLCLTCIVSG DPTPEISWLK NDQPVTFLDR YRMEVRGTEV TITIEKVNSE DSGRYGVFVK NKYGSETGQV TISVFKHGDE PKELKSM
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