Lipase member M (LIPM)

About Lipase member M

Lipase member M (LIPM) is a protein from Homo sapiens identified by UniProt accession Q5VYY2, 423 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Lipase member M
UniProt accession	Q5VYY2
Gene	LIPM
Organism	Homo sapiens
Length	423 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

lung adenocarcinoma · score 0.11
cutaneous melanoma · score 0.11
tumor necrosis factor receptor superfamily member 6 measurement · score 0.05
tauopathy · score 0.03
Crohn's disease · score 0.03
Leishmaniasis · score 0.02
cancer · score 0.02
Sepsis · score 0.01
central nervous system cancer · score 0.01
ulcerative colitis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VYY2-F1	alphafold	PREDICTED	88.91	—

Amino-acid sequence (423 residues)

MLETLSRQWI VSHRMEMWLL ILVAYMFQRN VNSVHMPTKA VDPEAFMNIS EIIQHQGYPC EEYEVATEDG YILSVNRIPR GLVQPKKTGS RPVVLLQHGL VGGASNWISN LPNNSLGFIL ADAGFDVWMG NSRGNAWSRK HKTLSIDQDE FWAFSYDEMA RFDLPAVINF ILQKTGQEKI YYVGYSQGTT MGFIAFSTMP ELAQKIKMYF ALAPIATVKH AKSPGTKFLL LPDMMIKGLF GKKEFLYQTR FLRQLVIYLC GQVILDQICS NIMLLLGGFN TNNMNMSRAS VYAAHTLAGT SVQNILHWSQ AVNSGELRAF DWGSETKNLE KCNQPTPVRY RVRDMTVPTA MWTGGQDWLS NPEDVKMLLS EVTNLIYHKN IPEWAHVDFI WGLDAPHRMY NEIIHLMQQE ETNLSQGRCE AVL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards