Muscleblind-like protein 2 (MBNL2)

About Muscleblind-like protein 2

Muscleblind-like protein 2 (MBNL2) is a protein from Homo sapiens identified by UniProt accession Q5VZF2, 373 residues long. MolForge cross-references it against 0 known binders and 220 disease associations.

Target properties

Protein name	Muscleblind-like protein 2
UniProt accession	Q5VZF2
Gene	MBNL2
Organism	Homo sapiens
Length	373 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (220)

Diseases linked to this target (Open Targets).

mathematical ability · score 0.47
neuroticism measurement · score 0.34
cystatin C measurement · score 0.34
viral load · score 0.34
age at menarche · score 0.33
diastolic blood pressure · score 0.31
cognitive function measurement · score 0.31
body fat percentage · score 0.30
Parkinson disease · score 0.30
intelligence · score 0.22

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q5VZF2-F1	alphafold	PREDICTED	64.89	—

Amino-acid sequence (373 residues)

MALNVAPVRD TKWLTLEVCR QFQRGTCSRS DEECKFAHPP KSCQVENGRV IACFDSLKGR CSRENCKYLH PPTHLKTQLE INGRNNLIQQ KTAAAMLAQQ MQFMFPGTPL HPVPTFPVGP AIGTNTAISF APYLAPVTPG VGLVPTEILP TTPVIVPGSP PVTVPGSTAT QKLLRTDKLE VCREFQRGNC ARGETDCRFA HPADSTMIDT SDNTVTVCMD YIKGRCMREK CKYFHPPAHL QAKIKAAQHQ ANQAAVAAQA AAAAATVMAF PPGALHPLPK RQALEKSNGT SAVFNPSVLH YQQALTSAQL QQHAAFIPTG SVLCMTPATS IDNSEIISRN GMECQESALR ITKHCYCTYY PVSSSIELPQ TAC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards