About Cystatin-9
Cystatin-9 (CST9) is a protein
from Homo sapiens identified by UniProt accession
Q5W186, 159 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | Cystatin-9 |
|---|
| UniProt accession | Q5W186 |
|---|
| Gene | CST9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 159 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (22)
Diseases linked to this target (Open Targets).
- cystatin C measurement · score 0.28
- blood protein measurement · score 0.23
- glomerular filtration rate · score 0.20
- benign prostatic hyperplasia · score 0.06
- Testicular regression syndrome · score 0.05
- 46,XX ovotesticular disorder of sex development · score 0.04
- cyst · score 0.03
- cystatin-SN measurement · score 0.02
- cystatin-SA measurement · score 0.02
- breast carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q5W186-F1 | alphafold | PREDICTED | 66.70 | — |
Amino-acid sequence (159 residues)
MSSPQRRKAM PWALSLLLMG FQLLVTYAWC SEEEMGGNNK IVQDPMFLAT VEFALNTFNV QSKEEHAYRL LRVLSSWRED SMDRKWRGKM VFSMNLQLRQ TVCRKFEDDI DNCPFQESLE LNNVRQGISF PQVHSCGCCM GCGVGTGAAD KAIPRDKGK
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