Triple QxxK/R motif-containing protein (TRIQK)

About Triple QxxK/R motif-containing protein

Triple QxxK/R motif-containing protein (TRIQK) is a protein from Homo sapiens identified by UniProt accession Q629K1, 86 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Triple QxxK/R motif-containing protein
UniProt accession	Q629K1
Gene	TRIQK
Organism	Homo sapiens
Length	86 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

type 2 diabetes mellitus · score 0.30
albuminuria · score 0.26
Ischemic stroke · score 0.26
schizophrenia · score 0.17
Antimigraine preparation use measurement · score 0.08
FEV/FVC ratio · score 0.05
age at first sexual intercourse measurement · score 0.05
ovarian carcinoma · score 0.01
tuberculosis · score 0.01
influenza · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q629K1-F1	alphafold	PREDICTED	74.38	—

Amino-acid sequence (86 residues)

MGRKDAATIK LPVDQYRKQI GKQDYKKTKP ILRATKLKAE AKKTAIGIKE VGLVLAAILA LLLAFYAFFY LRLTTDVDPD LDQDED

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards