Queuosine-tRNA galactosyltransferase (QTGAL)

About Queuosine-tRNA galactosyltransferase

Queuosine-tRNA galactosyltransferase (QTGAL) is a protein from Homo sapiens identified by UniProt accession Q67FW5, 346 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	Queuosine-tRNA galactosyltransferase
UniProt accession	Q67FW5
Gene	QTGAL
Organism	Homo sapiens
Length	346 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (35)

Diseases linked to this target (Open Targets).

eosinophil count · score 0.43
lymphocyte count · score 0.41
neutrophil percentage of leukocytes · score 0.35
urate measurement · score 0.32
bone density · score 0.32
testosterone measurement · score 0.28
asthma · score 0.28
lymphocyte percentage of leukocytes · score 0.28
monocyte count · score 0.16
low density lipoprotein cholesterol measurement · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q67FW5-F1	alphafold	PREDICTED	95.92	—

Amino-acid sequence (346 residues)

MQAHVSIILP VHNAEPWLDE CLRSVLQQDF EGTMELSVFN DASKDKSGAI IEKWRVKLED SGVHVIIGGH DSPSPRGVGY AKNQAVAQSS GSYLCFLDSD DVMMPQRVRL QHEAAVQHPS SIIGCRVRRD PPNSTERYTR WINQLTPEQL LTQVFTSNGP TVIMPTWFCS RAWFSHVGPF NEGGQGVPED LLFFYEHLRK GGGVIRVDQS LLLYRHHPQA ATHCVLETTI WTHRVRFLEE QALPRWAAFT IWNAGKQGRR LYRSLTAGSQ RKVVAFCDVD ENKIRKGFYC HEDSQERPKP RIPILHFRAA RPPFVICVKL DLTGGAFEDN LRSLHLQEGQ DFLHFS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards