About Maestro heat-like repeat-containing protein family member 7
Maestro heat-like repeat-containing protein family member 7 (MROH7) is a protein
from Homo sapiens identified by UniProt accession
Q68CQ1, 1323 residues long.
MolForge cross-references it against 0 known binders and
10 disease associations.
Target properties
| Protein name | Maestro heat-like repeat-containing protein family member 7 |
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| UniProt accession | Q68CQ1 |
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| Gene | MROH7 |
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| Organism | Homo sapiens |
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| Length | 1323 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (10)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.28
- free cholesterol measurement · score 0.27
- low density lipoprotein cholesterol measurement · score 0.27
- genetic disorder · score 0.12
- protein measurement · score 0.07
- ulcerative colitis · score 0.02
- chronic kidney disease · score 0.01
- hepatocellular carcinoma · score 0.01
- Tetralogy of Fallot · score 0.01
- dystocia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q68CQ1-F1 | alphafold | PREDICTED | 65.84 | — |
Amino-acid sequence (1323 residues)
MALSPGANLV FHEDPKMTPS PPSCGAPGLG SGTIPQPHPD MAQVPMLNLL PSPGLALVPD LNDSLSPVSG EASGLVSENT PRPDDSRAIA PASLQITSSC SGEALDLDSK DVSRPDSQGR LCPASNPILS PSSTEAPRLS SGNHPQSNSE DAFKCLSSKI FKLGQRNSNP SRHELNPFIR HHSREGLVLG HCISRPSSKA LLIPTSNSSL DLDSNPLLNM GSRNTSKLNL NVAPDSHGTL IPDTNETITL ASHNISESVS KGAFSTTWST SSKETMNVAS SGHSRSDLSV TITQASYVTL IPGSSYGISL HSSTHEPNST ISPPSCMTLI LGSNETLSLD SSLLFSDTST LTLSSQQDDA KDNSIHTVPL EENLESWSEM ASIKVGQFPL GFPISNPAGK DAVTLQGIPE GAFDEVTSCL VKVPEKTEGG NNMALVENVT TLQKSQDLLE AEGEKKTMIK KIMRQIQEEP LDSLSSSVRK QAMEILTQLS HTQPTLGMRE RSELVNVCVH SVFSLPSVQA MQEKDEAKAE TIQALYHQTL EALQTLLKAL FIEDPTPAGL KSILEALGPW MNSGKAHERA RAVNTNVSVL NHMLLTLPFF MPLGFPALGL LLGRLILHIG DPDEEIGCEA LDGIIILYTI LELQKRARDK EETNKKELYE SNKHFLGPYN PVSPCQNILR VIEEFGDFLG PQQIKDLLLA ALEGLKGSSE APGKDSREMM QLASEVMLSS VLEWYRHRAL EVIPEIMQGI YMQLSHIQEP RARQVALLPV SLLASSFMTE VVVALLMCPL PLNSNGAEMW RQLILCKPSC DVRDLLDLLL GSLKEKPVTK EGRASIVPLA AASGLCELLS VNSCMGRVRR IYPQLLLALL IQVHYHIGLN LPGCVAPPKD TKKGAQPSPF VPVRWVVKVV KTLLLRMGCS YETTFLEDQG GWELMEQVES HHRGVALLAR AMVQYSCQEL CRILYLLIPL LERGDEKHRI TATAFFVELL QMEQVRRIPE EYSLGRMAEG LSHHDPIMKV LSIRGLVILA RRSEKTAKVK ALLPSMVKGL KNMDGMLVVE AVHNLKAVFK GRDQKLMDSA VYVEMLQILL PHFSDAREVV RSSCINLYGK VVQKLRAPRT QAMEEQLVST LVPLLLTMQE GNSKVSQKCV KTLLRCSYFM AWELPKRAYS RKPWDNQQQT VAKICKCLVN THRDSAFIFL SQSLEYAKNS RASLRKCSVM FIGSLVPCME SIMTEDRLNE VKAALDNLRH DPEASVCIYA AQVQDHILAS CWQNSWLPHG NSWVCYSATT HRWSPSCENL PTSHQRRSWI MQALGSWKMS LKK
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