About HAUS augmin-like complex subunit 3
HAUS augmin-like complex subunit 3 (HAUS3) is a protein
from Homo sapiens identified by UniProt accession
Q68CZ6, 603 residues long.
MolForge cross-references it against 0 known binders and
157 disease associations.
Target properties
| Protein name | HAUS augmin-like complex subunit 3 |
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| UniProt accession | Q68CZ6 |
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| Gene | HAUS3 |
|---|
| Organism | Homo sapiens |
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| Length | 603 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (157)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.23
- neurodegenerative disease · score 0.22
- diastolic blood pressure · score 0.20
- systolic blood pressure · score 0.16
- hepatocellular carcinoma · score 0.11
- body height · score 0.11
- non-small cell lung carcinoma · score 0.11
- neoplasm · score 0.10
- cancer · score 0.10
- lymphocyte count · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q68CZ6-F1 | alphafold | PREDICTED | 78.64 | — |
Amino-acid sequence (603 residues)
MSCGNEFVET LKKIGYPKAD NLNGEDFDWL FEGVEDESFL KWFCGNVNEQ NVLSERELEA FSILQKSGKP ILEGAALDEA LKTCKTSDLK TPRLDDKELE KLEDEVQTLL KLKNLKIQRR NKCQLMASVT SHKSLRLNAK EEEATKKLKQ SQGILNAMIT KISNELQALT DEVTQLMMFF RHSNLGQGTN PLVFLSQFSL EKYLSQEEQS TAALTLYTKK QFFQGIHEVV ESSNEDNFQL LDIQTPSICD NQEILEERRL EMARLQLAYI CAQHQLIHLK ASNSSMKSSI KWAEESLHSL TSKAVDKENL DAKISSLTSE IMKLEKEVTQ IKDRSLPAVV RENAQLLNMP VVKGDFDLQI AKQDYYTARQ ELVLNQLIKQ KASFELLQLS YEIELRKHRD IYRQLENLVQ ELSQSNMMLY KQLEMLTDPS VSQQINPRNT IDTKDYSTHR LYQVLEGENK KKELFLTHGN LEEVAEKLKQ NISLVQDQLA VSAQEHSFFL SKRNKDVDML CDTLYQGGNQ LLLSDQELTE QFHKVESQLN KLNHLLTDIL ADVKTKRKTL ANNKLHQMER EFYVYFLKDE DYLKDIVENL ETQSKIKAVS LED
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