About Coiled-coil domain-containing protein 102B
Coiled-coil domain-containing protein 102B (CCDC102B) is a protein
from Homo sapiens identified by UniProt accession
Q68D86, 513 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein 102B |
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| UniProt accession | Q68D86 |
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| Gene | CCDC102B |
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| Organism | Homo sapiens |
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| Length | 513 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (29)
Diseases linked to this target (Open Targets).
- hypothyroidism · score 0.27
- myopic maculopathy severity measurement · score 0.26
- blood protein measurement · score 0.22
- metabolite measurement · score 0.22
- neurofibrillary tangles measurement · score 0.22
- inflammatory biomarker measurement · score 0.12
- YKL40 measurement · score 0.12
- protein measurement · score 0.11
- gut microbiome measurement · score 0.10
- neoplasm · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q68D86-F1 | alphafold | PREDICTED | 75.89 | — |
Amino-acid sequence (513 residues)
MNLDSIHRLI EETQIFQMQQ SSIKSRGDMV APASPPRDTC NTCFPLHGLQ SHAAHNFCAH SYNTNKWDIC EELRLRELEE VKARAAQMEK TMRWWSDCTA NWREKWSKVR AERNSAREEG RQLRIKLEMA MKELSTLKKK QSLPPQKEAL EAKVTQDLKL PGFVEESCEH TDQFQLSSQM HESIREYLVK RQFSTKEDTN NKEQGVVIDS LKLSEEMKPN LDGVDLFNNG GSGNGETKTG LRLKAINLPL ENEVTEISAL QVHLDEFQKI LWKEREMRTA LEKEIERLES ALSLWKWKYE ELKESKPKNV KEFDILLGQH NDEMQELSGN IKEESKSQNS KDRVICELRA ELERLQAENT SEWDKREILE REKQGLEREN RRLKIQVKEM EELLDKKNRL SANSQSPDFK MSQIDLQEKN QELLNLQHAY YKLNRQYQAN IAELTHANNR VDQNEAEVKK LRLRVEELKQ GLNQKEDELD DSLNQIRKLQ RSLDEEKERN ENLETELRHL QNW
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