Zinc finger protein 776 (ZNF776)

About Zinc finger protein 776

Zinc finger protein 776 (ZNF776) is a protein from Homo sapiens identified by UniProt accession Q68DI1, 518 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Zinc finger protein 776
UniProt accession	Q68DI1
Gene	ZNF776
Organism	Homo sapiens
Length	518 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

prostate carcinoma · score 0.11
prostate cancer · score 0.11
Familial prostate cancer · score 0.11
allergic rhinitis · score 0.04
chronic kidney disease · score 0.01
IGA glomerulonephritis · score 0.01
type 1 diabetes mellitus · score 0.00
Alzheimer disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q68DI1-F1	alphafold	PREDICTED	65.46	—

Amino-acid sequence (518 residues)

MAAAALRPPA QGTVTFEDVA VNFSQEEWSL LSEAQRCLYH DVMLENLTLI SSLGCWYGAK DETPSKQTLS IQQESPLRTH WTGVCTKKVH LWGMCGPLLG DILHQGTQHN QKLNGFGAYE KKLDDDANHH QDQKQHIGEK SYRSNAKGTS FVKNCKFHMS HEPFIFHEVG KDFLSSLRLL QQEDIHTSGK SNFETKHGIP LQGGKTHYIC GESTIPFSNK HSLVLHQRLL PREGPYVCSD SGKFTSKSNS FNNHQGVRTG KRPYQCGQCD ESFWYKAHLT EHQRVHTGER PYECGECDKS FSHKHSLVDH QRVHTGERPY ECDECGKSFS HKRSLVHHQR VHTGERPYQC GECGKSFNHK CNLIQHQRVH TGERPFECTA CGKLFRSNSH LKEHQRVHTG ERPYECKECR KSFRYKSHLT EHQRVHTGER PYECRECGKC FHQKGSLIQH QQIHSGERPH ECGECGKCFH QKGSLIRHQQ IHSGERPHEC GECGKCFRQK GNLIKHQRVH TGERHHEC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards