About Uncharacterized protein C18orf63
Uncharacterized protein C18orf63 (C18orf63) is a protein
from Homo sapiens identified by UniProt accession
Q68DL7, 685 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Uncharacterized protein C18orf63 |
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| UniProt accession | Q68DL7 |
|---|
| Gene | C18orf63 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 685 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- platelet count · score 0.19
- bilirubin measurement · score 0.12
- testosterone measurement · score 0.11
- sex hormone-binding globulin measurement · score 0.09
- creatinine measurement · score 0.07
- longevity · score 0.03
- metabolite measurement · score 0.03
- theta wave measurement · score 0.02
- blood protein measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q68DL7-F1 | alphafold | PREDICTED | 61.74 | — |
Amino-acid sequence (685 residues)
MNDSRQQSLF FITLPDLNKL CAVRIILSNK VADTEIRTIQ MKMCRQLLFL HQDILTSPVS GILNQIWVVM AIPFYKARKL NAYVEKYGAK MEAPQRVIPV ILQNCLSYSF MARLAPAWNR TGHLLIQGRD FLSQMGKQSA VVLNINVTET QVCLSIEACT IRLPAPELKE FEISQSIIKD FHANKHAVIE RHSILSNWCY VLPSMKMGQI INIFHAIPAA CPFHSYGDFQ RHWDALYGYK LPGDCGKIKI YCNIYFKMLG ERTFTYPLSC IRSQPMQFFP RVDSEVVLKS FLSDLKSKLP HICGFPIKMT SKPCYYTQEL TKPNIQEHKV KPPNLTTKKM LRASLTQATS RKPACAQSLL PCSVAVDHKV ELSVSQPTSG IFSALHLQPE SVQGRKKSLS IRAPQVHSEV LMPNRGNTQV QHTNLSSQSN ITPKFVPVFK NRLLQMNKNT SVLGSPKRKQ HDVTQSKLFS LKTSMIQHDK LNLGPAIKNR YSSNIQMQAA NNLNQENSRP LQEKNTESSE NMTKFPSSRG KSTVSLNKNK QLSNSAVFVV SNNNLGVVKS AVDFQMKGKE NLTGKGITQI LGKSHGSLKL KRQPHIFESD GETEDPRLLQ QQSENQAKEV GTSDHRLIVS KIAHRSKRKL CPESSKTSKK HHSDTVHYGQ SSSSKKQILD SDKSKLKKSL IIHNA
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