Zinc finger protein 626 (ZNF626)

About Zinc finger protein 626

Zinc finger protein 626 (ZNF626) is a protein from Homo sapiens identified by UniProt accession Q68DY1, 528 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

Target properties

Protein name	Zinc finger protein 626
UniProt accession	Q68DY1
Gene	ZNF626
Organism	Homo sapiens
Length	528 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (10)

Diseases linked to this target (Open Targets).

nasopharyngeal neoplasm · score 0.37
pancreatic adenocarcinoma · score 0.14
Down syndrome · score 0.05
endometrial carcinoma · score 0.02
chronic interstitial cystitis · score 0.01
breast cancer · score 0.01
bipolar disorder · score 0.01
hypertrophic cardiomyopathy · score 0.01
squamous cell carcinoma · score 0.00
post-traumatic stress disorder · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q68DY1-F1	alphafold	PREDICTED	71.52	—

Amino-acid sequence (528 residues)

MGPLQFRDVA IEFSLEEWHC LDTAQRNLYR NVMLENYSNL VFLGITVSKP DLITCLEQGR KPLTMKRNEM IAKPSVMCSH FAQDLWPEQS MKDSFQKVVL RRYEKCEHDN LQLKKGCISV DECKVHKEGY NELNQCLTTT PRKICQCDKY VKVLHQFPNS NGQKRGHTGK KPFKYIECGK AFKQFSTLTT HKKIHTGGKP YKCEECGKAF NHSCSLTRHK KIHTGEKPYK CEECGKAFKH SSTLTTHKRN HTGEKPYKCD KCGKAFMSSS TLSKHEIIHT EKKPYKCEEC GKAFNRSSTL TTHKIIHTGE KPYKCEECDK AFKYSYTLTT HKRIHTEDKP YKCEECGKAF KYSSTLTTHK RIHTGEKPYK CEECGKAFKR SSDLTTHKII HTGEKPYKCE ECGKAFKYSS NLTTHKKIHT GERPYKCEEC GKAFNQSSIL TTHRRIHTGE KFYKCEECGK AFKCSSNLTT HKKIHTGERP YKCEECGKAF NQSSILTTHE RIILERNSTN VKNVAKPSSG PHTLLHIR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards