Zinc finger protein 57 (ZNF57)

About Zinc finger protein 57

Zinc finger protein 57 (ZNF57) is a protein from Homo sapiens identified by UniProt accession Q68EA5, 555 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Zinc finger protein 57
UniProt accession	Q68EA5
Gene	ZNF57
Organism	Homo sapiens
Length	555 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

pancreatic adenocarcinoma · score 0.03
lung carcinoma · score 0.02
systemic juvenile idiopathic arthritis · score 0.01
rosacea · score 0.01
ulcerative colitis · score 0.01
neoplasm · score 0.01
esophageal squamous cell carcinoma · score 0.01
post-traumatic stress disorder · score 0.00
cancer · score 0.00
carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q68EA5-F1	alphafold	PREDICTED	68.79	—

Amino-acid sequence (555 residues)

MDSVVFEDVA VDFTLEEWAL LDSAQRDLYR DVMLETFRNL ASVDDGTQFK ANGSVSLQDM YGQEKSKEQT IPNFTGNNSC AYTLEKNCEG YGTEDHHKNL RNHMVDRFCT HNEGNQYGEA IHQMPDLTLH KKVSAGEKPY ECTKCRTVFT HLSSLKRHVK SHCGRKAPPG EECKQACICP SHLHSHGRTD TEEKPYKCQA CGQTFQHPRY LSHHVKTHTA EKTYKCEQCR MAFNGFASFT RHVRTHTKDR PYKCQECGRA FIYPSTFQRH MTTHTGEKPY KCQHCGKAFT YPQAFQRHEK THTGEKPYEC KQCGKTFSWS ETLRVHMRIH TGDKLYKCEH CGKAFTSSRS FQGHLRTHTG EKPYECKQCG KAFTWSSTFR EHVRIHTQEQ LYKCEQCGKA FTSSRSFRGH LRTHTGEKPY ECKQCGKTFT WSSTFREHVR IHTQEQLHKC EHCGKAFTSS RAFQGHLRMH TGEKPYECKQ CGKTFTWSST LHNHVRMHTG EKPHKCKQCG MSFKWHSSFR NHLRMHTGQK SHECQSYSKA FSCQVILSKT SESTH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards