About Dual specificity phosphatase 29
Dual specificity phosphatase 29 (DUSP29) is a protein
from Homo sapiens identified by UniProt accession
Q68J44, 220 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Dual specificity phosphatase 29 |
|---|
| UniProt accession | Q68J44 |
|---|
| Gene | DUSP29 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 220 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (29)
Diseases linked to this target (Open Targets).
- body height · score 0.41
- insomnia measurement · score 0.15
- refractive error measurement · score 0.12
- inflammatory bowel disease · score 0.09
- attention deficit hyperactivity disorder · score 0.09
- schizophrenia 15 · score 0.07
- attention deficit-hyperactivity disorder 8 · score 0.07
- body fat percentage · score 0.06
- Tourette syndrome · score 0.06
- Phelan-McDermid syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q68J44-F1 | alphafold | PREDICTED | 86.79 | — |
Amino-acid sequence (220 residues)
MTSGEVKTSL KNAYSSAKRL SPKMEEEGEE EDYCTPGAFE LERLFWKGSP QYTHVNEVWP KLYIGDEATA LDRYRLQKAG FTHVLNAAHG RWNVDTGPDY YRDMDIQYHG VEADDLPTFD LSVFFYPAAA FIDRALSDDH SKILVHCVMG RSRSATLVLA YLMIHKDMTL VDAIQQVAKN RCVLPNRGFL KQLRELDKQL VQQRRRSQRQ DGEEEDGREL
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